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OverviewDepuis plus de trente ans, des recherches ont t entreprises pour isoler et purifier la prot ine morphog n tique osseuse (BMP), une substance capable d'induire la formation ectopique d'os chez diff rentes esp ces animales. De r cents progr?'s dans les domaines de la biologie du d veloppement, la biologie mol culaire, la g n tique et la cicatrisation, ont d montr que les BMPs ont un r le primordial durant l'embryog n se, tant en ce qui concerne le syst me squelettique que la morphog n se d'autres tissus et organes. Leur pr sence en quantit infinit simale dans le squelette ne permettait pas d'envisager leur utilisation pour des reconstructions de d ficits osseux tant leur extraction et leur purification taient difficiles. Le d veloppement des techniques de clonage mol culaire a permis de produire ces mol cules en quantit illimit e et tr?'s pure par g nie g n tique sous forme de rhBMP-2 (la prot ine morphog n tique osseuse-2 recombinante humaine). Les essais pr cliniques et cliniques sur humains en chirurgie reconstructrice maxillofaciale et en implantologie sont extr mement positifs. Seule la question du support id al est encore en recherche. Full Product DetailsAuthor: Saloua DghoughiPublisher: Editions Universitaires Europeennes Imprint: Editions Universitaires Europeennes Country of Publication: United States Dimensions: Width: 15.20cm , Height: 0.70cm , Length: 22.90cm Weight: 0.168kg ISBN: 9786131593420ISBN 10: 6131593426 Pages: 108 Publication Date: 28 September 2011 Audience: General/trade , General Format: Paperback Publisher's Status: Active Availability: Not yet available  This item is yet to be released. You can pre-order this item and we will dispatch it to you upon it's release. Table of ContentsReviewsAuthor InformationTab Content 6Author Website:Countries AvailableAll regions |
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